There are many reasons for the instant disappearance of pins and needles pain in the chest, which may be caused by stomach cramps, pleurisy, costochondritis and other diseases. 1. Stomach cramp: because of excessive contraction of the smooth muscle of the stomach wall caused by overfeeding, strenuous exercise after meals, cold and other reasons, which will lead to epigastric pain, feeling like pins and needles in the chest instantly disappeared. 2. pleurisy: because of pathogen infection, injury, malignant tumors and other causes of inflammation of the pleura, often with fever, cough, cough sputum, chest pain, chest tightness and dyspnea as the main clinical manifestations, but also the symptoms of the instant disappearance of chest pain like pins and needles. 3. Costal chondritis: it is an inflammatory lesion that occurs in the rib cartilage area due to trauma and chronic strain injury, and it will also cause the symptoms of pinching pain in the chest to disappear instantly. The pain in the chest like a pinprick instantly disappeared may also be cardiac neurosis, coronary heart disease and other causes, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, to give targeted treatment or treatment, under the guidance of the doctor to carry out the treatment.