What does it mean when hepatitis B virus DNA is below the lower limit of detection?

Hepatitis B virus DNA below the lower limit of detection means that the hepatitis B virus is not currently replicating and does not require antiviral treatment. The hepatitis B virus DNA test is divided into a high-sensitivity test and a general test. The high-sensitivity test provides a more accurate determination of the hepatitis B viral load. If a normal hepatitis B virus DNA test is done and is below the lower limit of the test, a high-sensitivity DNA test is recommended. When the hepatitis B virus DNA test is below the lower limit of the test, it does not mean that it is always the case, but only that it is currently the case temporarily and needs to be checked regularly, more often than not every six months, for the purpose of rechecking to detect the rebound of the virus in time. If there is a rebound of the virus and the virus is elevated, if there is an indication for antiviral treatment, antiviral treatment should also be administered as soon as possible.