Daktarin, also known as miconazole nitrate ointment, is an antifungal drug, while erythromycin is an anti-infection drug. Perianal itching may be caused by hemorrhoids, sinusitis, and infection. In case of fungal infection, miconazole nitrate ointment can be given. If accompanied by bacterial infection, it can be treated with erythromycin. 1. Hemorrhoids: perianal itching may be caused by hemorrhoids, hemorrhoids lead to increased secretions, causing local irritation, can cause itching. You can use hemorrhoid cream, hemorrhoid suppository to apply under the guidance of the doctor. 2. sinusitis: sinusitis caused by perianal itching, need to improve lifestyle, with warm water bath, hemorrhoid suppository to help relieve. If the anal sinusitis has formed abscess, accompanied by anal papilla hypertrophy or hidden fistula, if necessary, through surgical treatment, such as anal sinus incision and drainage, anal sinus incision and hanging. 3. Infection: fungal infection caused by perianal itching, it is recommended to give antifungal drugs under the guidance of a doctor, such as miconazole nitrate ointment, ketoconazole ointment, which can inhibit and kill the fungus. If often scratching, will be secondary to bacterial infection, if necessary with erythromycin ointment topical application, anti-infection treatment. Perianal itching is related to a variety of factors, it is recommended to hospital dermatology, anorectal consultation, to understand the causes, targeted to give medication, specific drugs need to comply with the doctor’s instructions to use.