If prednisone is taken on time and in the amount prescribed by the doctor, it will generally not lead to abnormal liver function, but if prednisone is taken for a long time or in large amounts, it may lead to abnormal liver function. Therefore, patients are advised to follow medical advice when taking prednisone and other drugs, and to use prednisone with caution in patients with severe liver function impairment to avoid aggravation of the condition. Prednisone is the generic name for prednisone acetate, prednisolone, prednisolone acetate, hydrogenated prednisone and other drugs, which is an adrenocorticotropic hormone drug. Drugs such as prednisone are effective for the treatment of allergic and autoimmune inflammatory diseases such as rheumatoid arthritis, rheumatism, lupus erythematosus, thrombocytopenic purpura, granulocytopenia, and nephrotic syndrome. But usually, after taking the drug, it is mainly metabolized by the liver and kidneys. If you take prednisone for a long time or take too much, it will easily increase the burden of liver function and lead to abnormal liver function. If the patient suffers from liver damage, he or she needs to consult a professional doctor when taking the drug. Although prednisone drugs have good medicinal value, they should be taken in accordance with medical advice, in accordance with the dose, the course of treatment and on time. In addition, patients who are allergic to the ingredients of prednisone should be prohibited from taking prednisone to avoid allergic reactions after taking the drug, which can damage their health. If patients experience adverse reactions after taking prednisone drugs, such as nausea, vomiting, loss of appetite, muscle weakness, etc., they should stop taking the drug immediately and go to the hospital promptly.