Stent operation is not recommended for esophageal cancer patients after coughing up blood, which may cause increased bleeding or even shock, and it is necessary to carry out hemostatic treatment first. Coughing up blood indicates that the esophageal cancer tumor and its surrounding tissues have obvious blood vessel breakage and bleeding symptoms, at this time, the coagulation function of the body will drop dramatically, thus causing coagulation disorder, and if stent intervention is accepted, the amount of bleeding may be increased, which may cause anemia or hemorrhage and other symptoms, and in serious cases, hemorrhagic shock may be caused, which may endanger the life. Patients with esophageal cancer coughing up blood should be treated with hemostatic therapy immediately, and they can take proper hemostatic drugs under doctor’s guidance to stop bleeding quickly, such as vitamin potassium or thrombin. If the bleeding volume is large or the bleeding wound surface is large, endoscopic hemostatic operation is needed to quickly suture the blood vessels to achieve the fastest hemostatic effect, which can effectively reduce the bleeding volume and protect esophageal tissues. After coughing up blood, esophageal cancer patients should be treated for coughing up blood before considering subsequent stent operation or other treatment options.