If there are hard lumps after hyaluronic acid filling in a short period of time, they can be softened by themselves, if the hard lumps are not softened in a long period of time, patients should consult doctor as soon as possible, according to the specific reasons, they can be treated by injection of dissolving enzyme or drugs. 1. Self-softening: if the patient in the injection of hyaluronic acid within a short period of time, hard lumps, mostly due to local inflammatory reaction or local bleeding, at this time the patient should avoid massage, hot or cold compresses, in the case of non-treatment, usually about 2 weeks will be softened and absorbed on their own. 2. Injecting dissolving enzyme: if the hard lumps do not disappear after one month, the possibility of self-absorption is not big, if the patient is filled with regular hyaluronic acid, then the hyaluronic acid can be decomposed by local injection of dissolving enzyme, after decomposition, we can combine with the patient’s request to consider whether to use the small molecule hyaluronic acid to fine-tune it again. 3. Medication: If the hard lump is formed by bacterial infection pus accompanied by redness, swelling and hot pain, you need to apply erythromycin ointment, mupirocin ointment and other anti-infective treatment, the serious need to drain the abscess puncture, and supplemented with oral antibiotic treatment. All of the above medications should be used under the guidance of a doctor, avoid self-medication.