Not feeling hungry after taking oral medication for GERD may be an adverse reaction caused by acid-suppressing drugs such as omeprazole, or it may be caused by eating too much in general and incomplete emptying of stomach contents. Patients with reflux esophagitis usually take drugs that inhibit gastric acid secretion, such as proton pump inhibitors like omeprazole or H₂ receptor blockers like ranitidine, in order to alleviate symptoms such as acid reflux and heartburn. However, while inhibiting the secretion of gastric acid, the above drugs will also affect the patient’s digestive function, which will reduce the patient’s ability to digest food and even lead to dyspepsia, resulting in the phenomenon of not feeling hungry. If the patient eats too much, resulting in incomplete discharge of stomach contents, the phenomenon of not feeling hungry may also occur. If the patient has the above situation for a long time, it is recommended to consult a doctor in time to clarify the cause of the disease under the guidance of a professional physician, so as to avoid delaying the condition.