The significance of the Male Sex Hormone Six test is to test the etiology of male infertility and male sexual dysfunction. The Male Sex Hormone Six test mainly includes follicular estrogen, luteinizing hormone, prolactin, androgen testosterone, progesterone and estrogen estradiol, which is a gonadotropin secreted by the pituitary gland. It is mainly checked during puberty, planning for pregnancy and menopause and is usually done in the morning on an empty stomach between 8 and 9 o’clock. A relatively low level of androgen testosterone and estradiol may indicate poor libido and erectile function; a high level of androgen testosterone may indicate hypersexuality; and problems with luteinizing hormone, follicular estrogen, or androgen testosterone are usually indicative of pubertal testicular dysplasia or tumor-related disorders. If you experience any of these problems and are in doubt, it is advisable to consult a medical professional.