Acne medically refers to acne, a chronic inflammatory skin disease of the sebaceous glandular units of hair follicles. The causes of acne around the jawline are considered to be related to abnormal perifollicular cellular keratinization, overpopulation of Propionibacterium acnes, and high androgen levels, etc. Topical medications, systemic medications, and home care are available for treatment. 1. Abnormal keratinization of perifollicular cells: Some patients may suffer from abnormal keratinization of perifollicular cells, so the opening of the hair follicle becomes smaller, narrower or even blocked, which may easily cause acne around the jawline. Topical retinoic acid creams, such as Adapalene, can be used to dissolve acne and improve follicular duct keratinization. 2. Propionibacterium acnes overgrowth: When the acne bacteria overgrowth, it will also cause acne around the angle of the jaw. It can be used through the use of benzoyl peroxide, which slowly releases the new eco-oxynuclear benzoic acid, which has the effect of killing the acne bacteria and dissolving acne. 3. High androgen level: some patients may have too much androgen level in their body, which induces acne around the angle of the jaw, through oral contraceptives, spironolactone and other drugs to play the role of anti-androgen. It is recommended that the patient to the hospital in a timely manner, clear causes, under the guidance of the doctor to give targeted treatment, the use of drugs need to follow the doctor’s instructions.