Systolic hypertension alone with reduced diastolic blood pressure is most often seen in older patients with hypertension. Elderly hypertensive patients on antihypertensive therapy have reduced diastolic blood pressure to below 70 mmHg, although systolic blood pressure has not yet reached the target. Quiet, awake, and without the use of antihypertensive drugs under the conditions of standard measurement methods, at least three non-same-day blood pressure measurements, systolic blood pressure ≥ 140 mmHg and diastolic blood pressure < 70 mmHg, that is, high pressure high and low pressure low, also known as diastolic blood pressure reduced simple systolic hypertension or bipolar differentiated hypertension, is another common form of hypertension in the elderly, mainly associated with increased arterial stiffness and decreased elasticity. 1. Increased stiffness and decreased elasticity of large arteries in patients with pure systolic hypertension. During ventricular systolic ejection, the pressure in the aorta rises, resulting in increased systolic pressure; during ventricular diastole, the arterial elasticity retraction capacity is insufficient, resulting in decreased diastolic pressure; increased systolic pressure and decreased diastolic pressure result in increased pulse pressure. 2, diabetes, hyperlipidemia, metabolic syndrome, certain rheumatic immune diseases and other diseases will promote vascular inflammation and promote the process of atherosclerosis. 3, diastolic blood pressure is reduced in simple systolic hypertension, patients maintain the ideal level of diastolic blood pressure is the challenge of treatment. Great attention must be paid to the changes in diastolic blood pressure when lowering systolic blood pressure to avoid lowering diastolic blood pressure even lower in the process of lowering blood pressure. When diastolic blood pressure is lower than the level required to maintain perfusion of vital organs, the risk of cardiovascular disease increases. 4, for high pressure high and low pressure low, life attention to develop good habits, and actively treat diseases that lead to atherosclerosis; in the process of hypertension treatment to take into account the high pressure and low pressure situation.