Ankle edema, first of all, to clarify the cause of the disease, the common causes are heart or kidney and other internal diseases caused by edema, trauma factors caused by edema, lower limb vascular disease, should be directed to the cause of the general treatment, medication or surgical treatment, and so on. 1. Internal diseases: such as coronary heart disease, nephritis, etc. can cause ankle edema. (1) Coronary heart disease: it can lead to cardiac insufficiency and cause low level edema, which can be treated with drugs such as isosorbide mononitrate for vasodilatation, furosemide and other drugs for diuresis, digoxin and other drugs for cardiac strengthening, and rest should be paid attention to at the same time. (2) Nephritis: Nephritis mostly leads to sodium retention, or combined with hypoproteinemia, causing edema symptoms, can be given anti-inflammatory drugs such as methylprednisolone, methotrexate and other immunosuppressive drugs, if kidney failure occurs, also need to consider dialysis and other special treatments. 2. Trauma: first of all, the affected limbs need to be strictly braked, can not go down to the ground weight-bearing activities, early can be cold compresses, edema is serious, can be static mannitol, or oral edema drugs, such as Diosmin tablets and other drugs. 3. Lower extremity vascular disease: such as varicose veins of the lower extremities, can also cause edema of the lower extremities, the symptoms of light can wear compression stockings, reduce standing, can also be taken orally to improve the blood flow of the lower extremities of the drug, such as Mai Zhi Ling. If the symptoms are mild, you can wear elastic stockings to reduce standing, or take oral medication to improve blood flow in the lower limbs, such as Mazolin. There are many factors that cause ankle edema, it is recommended to consult the hospital in time, and improve the relevant examination, under the guidance of the doctor for targeted treatment.