Diabetes treatment, including diet, exercise, medication, blood glucose self-monitoring and diabetes education, of which medication is an important part. Medication includes oral drugs and injectable drugs, oral drugs are divided into the following categories: 1, sulfonylurea insulin stimulants, including glimepiride, glipizide, damacen, glipizide, which are sulfonylurea stimulants, non-sulfonylurea stimulants called glinides, including reglanet, nateglinide and miglinide, which are also stimulants; 2, biguanide drugs, which can reduce insulin resistance, improve insulin sensitivity, can reduce body weight, including metformin and hypoglycemia, hypoglycemia due to its side effects, easy to induce lactic acidosis, basically not used, now using biguanides is metformin; 3, glycosidase inhibitors, including acarbose, miglitol, voglibose, which can delay the absorption of intestinal glucose, so reduce postprandial blood sugar is more obvious; 4, thiazolidinedi ketones, which can enhance the sensitivity of insulin and improve the function of pancreatic β-cells, mainly pioglitazone, and these drugs should be used with attention to their side effects because they are easy to cause sodium and water retention, so patients with cardiac insufficiency should avoid using them as much as possible; 5. New oral hypoglycemic drugs include DPP-4 inhibitors, like sitagliptin, vildagliptin, alogliptin, etc. These drugs can play a role in reducing In addition to lowering blood glucose, these drugs have a certain protective effect on the heart and kidneys, especially for patients with combined heart disease, which can reduce the rate of heart failure hospitalization and reduce the mortality rate of cardiovascular disease, and also have a protective effect on diabetic nephropathy. Injectable drugs include: insulin, which is divided into ultra-short-acting, short-acting, medium-acting and long-acting insulins, and the use of insulin should be decided according to the patient’s specific situation; 8. These drugs can reduce body weight, suppress appetite, improve insulin sensitivity, and have a protective effect on cardiovascular disease. The drug treatment of diabetes includes oral drugs and injections, and different drugs should be selected according to different conditions to ensure that blood sugar is controlled to the ideal range and to avoid acute and chronic complications.