Two and a half year old baby runny nose coughing for four days to play the needle to drink medicine, not good may not be symptomatic treatment, need to go to the hospital for further examination, clear cause targeted treatment, common causes may be and bacterial infections, viral infections, mycoplasma infections and other factors related. 1. Bacterial infection: if the baby through the blood test is clearly a bacterial infection, you need to use cefixime, amoxicillin and other antibiotics for treatment. 2. Viral infections: viral infections need to be treated with drugs such as ribavirin or oral antiviral solution. 3. mycoplasma infection: mycoplasma infection preferred macrolide antibiotic drugs, such as erythromycin, erythromycin, azithromycin and so on. Two and a half year old baby runny nose coughing for four days to play the needle to drink medicine, is not good, may also be other causes, such as allergies, etc., it is recommended that timely medical treatment. All of the above drugs are taken under the guidance of a doctor, not to be used on their own.