Patients with stage IV chronic kidney disease are more serious and their condition is irreversible, often with symptoms of hypertension, secondary hyperparathyroidism, acidosis, and renal anemia. Chronic kidney disease is categorized into five stages according to the degree of impairment of glomerular filtration rate. Stage IV means that the patient’s glomerular filtration rate is 15-29 ml/min-1.73m², and the kidney function has been mostly lost, which needs to be prepared for renal replacement therapy, and is also known as pre-uremia. Chronic Kidney Disease Stage IV means that various complications have already appeared, and will be in any emergency situation, there may be a sudden and drastic decline in kidney function, and a critical situation. Chronic Kidney Disease Stage IV is a more serious condition, and patients are advised to go to the hospital in time for standardized treatment under the guidance of doctors to slow down the progress of the disease.