Why does Helicobacter pylori have diarrhea on a quadruple pill?

Patients using quadruple therapy to treat H. pylori may experience diarrhea due to adverse drug reactions, but diarrhea symptoms may also be caused by changes in the patient’s condition.
1. Adverse drug reactions: H. pylori quadruple therapy refers to a proton pump inhibitor, a bismuth agent plus two antibiotics for treatment, commonly used drugs include potassium citrate, pantoprazole, amoxicillin, metronidazole, etc., most of which can lead to diarrhea, abdominal distension, nausea, vomiting and other adverse reactions.
2. Changes in condition: Helicobacter pylori infection can lead to peptic ulcer, dyspepsia and other diseases, some of which can basically lead to diarrhea, abdominal distension, abdominal pain and other discomforts, and may cause diarrhea if the patient’s condition changes during the use of tetracycline therapy.
Drugs need to be used under the guidance of a physician, it is recommended that patients to the regular hospital gastroenterology and related departments to consult, under the guidance of the doctor for targeted treatment.