It takes three days to have a medical abortion, and on the third day, the stomach will hurt, the pain is usually slightly more severe than menstrual cramps, but the vast majority of women can tolerate it. The reason for the belly pain on the third day is because of the Misoprostol medication. Misoprostol induces contractions, which cause the uterus to contract, and when there are contractions, the patient will experience significant abdominal pain. When the gestational sac is expelled, the abdominal pain will be significantly relieved.