Jaundice in newborns does not require too much stress, about 85% of full-term infants and the vast majority of preterm infants in the neonatal period will have a temporary increase in total bilirubin, most of them are physiological, do not need special treatment, usually within 2 weeks to subside naturally. For a small proportion of pathologic jaundice, timely intervention is needed. For full-term infants with serum total bilirubin levels greater than 205 μmol/L due to a variety of reasons, phototherapy can be given, in which infants are placed in a phototherapy box under the action of light so that unconjugated bilirubin is converted into water-soluble substances, which are excreted in the bile and urine. In addition, it is also necessary to treat the cause of the disease. Hemolytic jaundice caused by mother-infant blood group incompatibility is pathological jaundice, which can be treated with blue light irradiation, and in severe cases, blood exchange can be given; in case of breast milk jaundice, the jaundice can be significantly reduced after stopping breastfeeding for 24-48 hours, and in case of jaundice due to congenital obstruction of bile ducts, the patient should be treated with surgery as soon as possible.