Intestinal tuberculosis cannot be diagnosed simply. Biopsy of the intestinal mucosa can confirm the diagnosis, but it is an invasive operation. Other than that, the diagnosis can be confirmed by combining the patient’s medical history, clinical symptoms and auxiliary examinations, and diagnostic treatment if necessary. Intestinal tuberculosis should be considered when the patient has extraintestinal tuberculosis (e.g. tuberculosis), with abdominal pain, diarrhea, constipation, etc., accompanied by symptoms of tuberculosis intoxication, such as low fever, night sweating (sweating abnormally after falling asleep, but stops after waking up); barium meal examination reveals jumping signs, ulcers, intestinal deformities, stenosis and other manifestations; colonoscopy reveals ileocolic inflammation, ulceration, polyps, or stenosis and so on. For highly suspected cases, anti-tuberculosis treatment can be tried for 2~6 weeks, and the diagnosis of intestinal tuberculosis can also be confirmed if the symptoms improve significantly. The diagnosis of intestinal tuberculosis can be confirmed if a biopsy of the intestinal mucosa reveals caseous granulomas or if bacillus antacidus is found in the biopsy tissue. Early lesions of intestinal tuberculosis are reversible. If the diagnosis of intestinal tuberculosis is confirmed or highly suspected, it should be actively treated at an early stage in order to achieve the best prognosis.