Syphilis can be self-tested by whether there is contact with syphilis patients and physical symptoms. However, it is not recommended to self-test, if there is high-risk sexual behavior or suspected of syphilis infection, it is recommended to consult a doctor in time, early standardized treatment. Self-testing for syphilis is to check whether you have had sexual contact with a syphilis patient, whether you have used the goods of a syphilis patient, and so on, and physically, to check whether there are lesions such as erythema, pimples, hard nodules, and so on, etc. The clinical manifestations of syphilis are divided into three categories. The clinical manifestations of syphilis are divided into three stages. 1. Stage I syphilis: it often manifests itself in the form of a hard chancre and sclerosing lymphadenitis, and there are usually no systemic symptoms. The chancre develops on the external genitalia as a painless erythema, which then develops into papules, hard nodules and ulcers. The inguinal lymph nodes are often enlarged 1 to 2 weeks after the occurrence of the chancre and are painless and without redness or ulceration. 2. Stage II syphilis: bacteremia is formed, spreading throughout the body and is highly infectious. It is characterized by skin and mucous membrane damage, including syphilis rash and flat warts, bone and joint damage, eye damage, nerve damage, and visceral syphilis. 3. Third stage syphilis: skin damage is mainly nodular syphilis rash and syphilitic gumma, bone syphilis, eye syphilis, cardiovascular syphilis, neurosyphilis. When suspected of syphilis, it is recommended to actively go to the hospital, after a clear diagnosis for targeted treatment.