Inflammation of subcutaneous lipoma, the cause is related to skin damage, secondary infection and other factors. 1. Skin damage: If the skin in the area of subcutaneous lipoma is stimulated by enlightenment or other objects, it may cause skin damage. If the skin area comes into contact with clothes or water containing dirt, it may lead to invasion of bacteria or germs, which may cause inflammation of subcutaneous lipoma and ulceration of the injured area. 2. Secondary infection: if the subcutaneous lipoma site has bruises and so on, and then there is infection, it will spread to the lipoma and lead to inflammation of the lipoma. The main manifestations are local redness, swelling, pain, fever and other symptoms. With the gradual aggravation of the infection, the redness, swelling and pain will become bigger and bigger, and in serious cases, it may be accompanied by purulent secretion and other phenomena. Once the subcutaneous lipoma is inflamed, it is necessary to consult a doctor in time and actively cooperate with the doctor’s treatment, so as not to aggravate the symptoms.