Acromegaly is a kind of motor neuron disease, mainly involving upper and lower motor neurons, manifested by progressive muscle atrophy and muscle weakness, and usually does not have sensory abnormalities. If patients have sensory abnormalities, such as numbness of the hands, there may be other causes, the cause should be analyzed to treat the primary disease, and symptomatic treatment if necessary. 1. If the hands are numb, it may be peripheral neuritis or cervical spondylosis compression of the nerve, active treatment of the primary disease at the same time, nutritive nerve therapy, commonly used nutritive nerve drugs such as adenosylcobalamin and methylcobalamin. 2. If the numbness of one hand, it may be caused by cervical spondylosis compression of the nerve, or cerebrovascular disease, such as cavernous cerebral infarction, there may be numbness of one hand, one foot, first of all, we should actively treat cerebrovascular disease, including aspirin anti-platelet aggregation, atorvastatin lipid stabilization plaque, while nutritional nerve therapy, the application of vitamin B12, adenosylcobalamin and methylcobalamin and so on. There is no effective cure for acromegaly, mainly symptomatic supportive treatment, you can apply riluzole, to improve the symptoms and slow down the progress of the disease has a certain effect.