Shoulder and neck pain when stomach distension occurs may be related to cholecystitis, pancreatitis, gastroesophageal reflux disease, stomach cancer and so on. 1. Cholecystitis: For patients suffering from cholecystitis, if it affects the stomach, gastric distension will also occur, and the pain can also radiate to the neck and shoulders. 2. Pancreatitis: For patients suffering from pancreatitis, the onset of the disease will not only be accompanied by severe pain in the upper abdomen, but also may be radiated to the back of the shoulders, and then appeared in the neck and shoulder pain symptoms, especially the left side of the neck and shoulder pain is more obvious. 3. Gastroesophageal Reflux Disease (GERD): Generally, patients will have typical symptoms such as heartburn, acid reflux, retrosternal pain, etc., and the pain is usually located at the back of the sternum or the lower part of the rapier, which can radiate to the shoulder and cause shoulder and neck pain. 4. Gastric cancer: For patients suffering from gastric cancer, especially in advanced stage, it will cause damage to gastric mucosa and symptoms such as stomach distension, pain, etc. When the cancer cells are transferred to the shoulder through lymphatic transfer, shoulder and neck pain symptoms will also appear. There are many reasons causing shoulder and neck pain when stomach distension occurs, and when it occurs frequently, it is recommended to consult doctor in time, carry out relevant examinations, and follow doctor’s instruction for treatment after clarifying the cause of the disease.