Cleanliness IV degree generally refers to the cleanliness IV of vaginal secretions, indicating that the vaginal flora is imbalanced and there are a large number of leukocytes and miscellaneous bacteria in the vagina, etc. This situation is related to factors such as poor lifestyle, long-term use of medication, and invasion of exogenous pathogens. 1. Bad lifestyle, such as frequent vaginal douching, long-term use of various gynecological lotions to clean the vulva and vagina, and too frequent sex, can reduce or disappear the lactobacilli in the vagina, and leukocytes and miscellaneous bacteria multiply, resulting in secretion cleansing degree IV. 2. Long-term medication, long-term use of broad-spectrum antibiotics, such as amoxicillin, ceftriaxone sodium, etc. can inhibit the growth of vaginal lactobacilli, resulting in abnormal secretion cleanliness. 3. Invasion of exogenous pathogens, decreased immunity, sexual transmission, etc. can cause trichomonas, pseudofilamentous yeast and other reproduction. Overpopulation of pathogenic bacteria can also destroy the vaginal flora, resulting in abnormal cleanliness, which is often accompanied by trichomonas and pseudofilamentous yeast positivity. Under normal circumstances, vaginal secretion cleanliness should be I∽II, cleanliness III∽IV need to correct lifestyle, if accompanied by vulvar itching, burning pain or test results suggest pathogenic microbial infections, should be based on the specific circumstances of the doctor to follow the reasonable treatment.