The HFMD vaccine is mainly for children, especially younger children who have a fever from the HFMD vaccine, and generally the fever symptoms can gradually recover in 3-5 days. However, it is important to monitor the body temperature during the fever and observe the child’s mental state, and take the child to the hospital immediately if the mental state is not good. If the temperature is not too high, below 38.5℃, the child can be treated with pediatric black beetle fever granules, pediatric cold and flu fever granules or antelope granules, which not only have a mild fever-reducing effect, but also have a certain antiviral effect. After the hand, foot and mouth vaccine, it is likely that the child’s resistance is weak, causing viral infections, the use of the above-mentioned Chinese medicine is also more effective. If the temperature of the fever is relatively high, more than 38.5 ℃, in addition to the need to use ibuprofen suspension to reduce fever, but also need to immediately go to the hospital to the child, especially under three years old children occur hand, foot and mouth disease is also more dangerous.