The best way to lower bilirubin does not exist. Elevated bilirubin may be caused by hepatitis, cirrhosis of the liver, gallbladder stones and other diseases, which need to be treated according to the cause of the disease, such as medication, surgery and so on. 1. Hepatitis: Liver cells suffer a lot of destruction, which will lead to elevated bilirubin. For patients with hepatitis, if it is viral hepatitis, such as hepatitis B, they should take antiviral drugs such as lamivudine and entecavir as prescribed by the doctor. If it is alcoholic hepatitis, quit drinking in time. If it is drug hepatitis, stop using the suspected drugs. 2. Cirrhosis: If it is cirrhosis that leads to elevated bilirubin, patients should take glycyrrhizic acid preparation, bicyclic alcohol and other liver-protecting drugs to control liver inflammation and necrosis. At the same time, follow the doctor’s instructions to take Anluohua Fibrin Pill, compound turtle shell soft liver tablets and other drugs for anti-fibrosis treatment. If in the end stage of cirrhosis, liver transplantation is needed. 3. Gallbladder stones: When gallbladder stones lead to bile duct obstruction, bile cannot be excreted smoothly, which will also lead to elevated bilirubin. Once diagnosed with gallbladder stones, surgical treatment should be the mainstay, with cholecystectomy being the first choice. The best way to lower bilirubin does not exist. It is recommended that patients seek medical examination to clarify the diagnosis and cooperate with the doctor for treatment. Drugs need to be used under the guidance of a professional physician, do not self-medicate arbitrarily.