It is possible for low platelets to affect blood clotting. This is because the body’s blood clotting system is caused by 3 main factors. I. Factors of the blood vessel wall. Second, the factors of platelets. Third, abnormal coagulation factors. Abnormalities in the above 3 areas can lead to abnormal coagulation. If there is a mild decrease in platelets, the chance of bleeding is not very high. However, if platelets are significantly reduced, the risk of bleeding is still high. With lowered platelets, bleeding mostly manifests as bleeding from the skin and mucous membranes. For example, bleeding spots and petechiae on the skin. In addition, hematuria, hemoptysis, etc. can also occur. In severe cases, brain hemorrhage can occur.