Paroxysmal pain in the thoracic spine may be caused by small joint disorder of the thoracic spine, spinous processes of the thoracic spine, herniated discs, tuberculosis of the thoracic spine, cervical spondylosis, and cardiac diseases, which can be treated by physical therapy, hot compresses, oral medications, and surgeries. 1. Small joint disorder of thoracic vertebrae: when small joint disorder of thoracic vertebrae occurs, paroxysmal pain in the thoracic vertebrae will appear, and physiotherapy, hot compresses and other treatments can be carried out to alleviate it. 2. Thoracic spondylitis: Thoracic spondylolisthesis can cause paroxysmal pain in the thoracic spine due to strain and injury. Physical therapy and oral non-steroidal drugs such as ibuprofen can be used. It can also be treated with injection closure. 3. Herniated disc: when the thoracic disc is herniated, there may be the symptom of compression of the nerve, which may cause localized severe paroxysmal pain. In this case, manipulation or incision should be used under the advice of the doctor to relieve the compression. 4. Thoracic spine tuberculosis: Thoracic spine tuberculosis can lead to cold abscesses around the thoracic spine, and in the later stage of tuberculosis, there will be pain in the spinous processes fixed in the plane of the spinal lesion as well as radiating pain, which should be treated with anti-tuberculosis therapy, and clinically used isoniazid, rifampicin, and ethambutol for quadruple combination drug therapy. 5. Cervical spondylosis: cervical spondylosis will appear to involve the thoracic spine part of the paroxysmal pain, the treatment needs to use non-steroidal anti-inflammatory drugs such as celecoxib. In severe cases, surgical removal of the intervertebral disc is required to relieve the symptoms. 6. Heart disease: coronary heart disease and angina will radiate to the thoracic spine, causing thoracic spine paroxysm, the clinical need for coronary angiography to find the cause of treatment. Thoracic spine paroxysm should go to the hospital in time, do not delay the condition. All of the above drugs should be used under the guidance of a physician.