Gout patients with swollen joints can be eliminated by colchicine, non-steroidal anti-inflammatory drugs and glucocorticoid symptomatic treatment. 1. Colchicine: Colchicine is the first choice and commonly used drug in acute gout attack, it should be given in low dose, which can rapidly relieve the symptoms of joint swelling in patients with acute gout attack. 2. Non-steroidal anti-inflammatory drugs: diclofenac, ibuprofen, indomethacin, etoricoxib and other non-steroidal anti-inflammatory drugs can inhibit the cyclooxygenase enzyme in the patient’s body to alleviate the symptoms of joint swelling during the acute attack of gout, but the contraindications to the use of the corresponding drugs need to be ruled out before use. 3. Glucocorticoid: Colchicine and non-steroidal anti-inflammatory drug treatment is ineffective or there are contraindications to these two drugs can be used under the guidance of a physician prednisone, dexamethasone and other glucocorticoid therapy. Drugs need to be used under the guidance of a physician, it is recommended that gout patients with symptoms of joint swelling to the rheumatology and immunology department of the regular hospital, under the guidance of the doctor to use drugs.