High Ca724 and low pepsinogen 1 suggest possible digestive disorders. Ca724 is a glycoprotein antigen, and the normal value is usually between 0-6.7 μg/L. Ca724 is mainly used for the diagnosis of malignant tumors in the stomach, other tumors such as pancreatic cancer, ovarian cancer, lung cancer, etc. may also show markedly increased Ca724, benign diseases such as pancreatitis, hepatitis, ovarian cysts can also lead to increased Ca724, and a small number of normal people, such as the elderly, women during menstruation can also show increased Ca724. Pepsin cause is mainly secreted by the main cells and mural cells in the fundus of the stomach, and the normal value range is 60-240ng/ml. When the secretion ability of pepsinogen test is low, it suggests that the secretion of gastric acid is too low, and it is considered that there may be atrophic gastritis, intestinal epithelial hyperplasia, heterotopic hyperplasia, and atypical hyperplasia, which need to be further combined with gastroscopy and pathological tissue testing to determine whether gastric epithelial hyperplasia, gastric mucosal atrophy, and so on, exists. Abnormalities in Ca724 and pepsinogen tests should be treated promptly in the gastroenterology department of a regular hospital.