A small number of fibrotic foci in both lungs and the thickness of pleural thickening is small, the patient does not have any clinical symptoms, generally not serious. If the patient’s fibrosis foci involve most of both lungs and the pleural thickening affects normal breathing, the patient has clinical symptoms such as dyspnea and cyanosis, which is more serious. Specific analysis is as follows: 1. Not serious: the power of lung respiration comes from the difference between internal and external pressure and the expansion of the thorax, the thorax pulls the lungs to expand, and the gas enters the lungs for exchange, and the site of gas exchange is mainly in the alveolar tissue. If a small number of fibrotic foci in both lungs and the thickness of pleural thickening is small, which has less influence on respiration, and the patient does not have any clinical symptoms, it is generally not serious. 2. More serious: as mentioned above, if a large number of fibrosis foci in both lungs, the effective area of alveolar gas exchange is reduced; and pleural thickening, the thorax can not pull the lungs to expand, the air into the lungs is reduced, which seriously affects the lung function, and ultimately leads to a decrease in the ratio of alveolar ventilation and blood flow, tissue hypoxia, and symptoms of respiratory distress, cyanosis, etc., the situation is more serious. It is recommended that patients go to regular hospitals as early as possible for lung function and lung CT and other tests to clarify the severity of the disease, treat the primary disease as early as possible, control the progression of pulmonary fibrosis and pleural thickening, and maintain the respiratory function of the lungs as much as possible to prolong the life time. Do not delay the disease and miss the treatment.