There is no “best” medication for asthma treatment, it needs to be chosen according to the patient’s personal situation, the most appropriate is the best. When asthma is in acute attack, short-acting β2 agonists such as salbutamol and terbutaline, intravenous glucocorticosteroids such as methylprednisolone, theophyllines such as aminophylline, and short-acting anticholinergic drugs such as ipratropium bromide can be used, and when the effect is unsatisfactory, mechanical ventilation can be given. Inhaled glucocorticosteroids such as budesonide, long-acting β2 agonists such as salmeterol and formoterol, long-acting anticholinergic drugs such as tiotropium bromide, leukotriene modulators such as montelukast sodium, and small-dose theophyllines can be applied during the chronic remission period. As the indications, contraindications and adverse effects of different drugs are different, doctors will choose the most appropriate drug for treatment according to the degree of the patient’s condition and the therapeutic effect. Patients should follow the doctor’s instructions and avoid using or stopping the medication on their own. In addition, asthma patients should pay attention to the living environment and maintain healthy living habits.