Many people will be very nervous after finding elevated tumor markers, thinking that they are suffering from “tumor”, in fact, they should not panic at this time, and need to exclude whether it is really a “tumor”. Clinically, through collecting blood specimen, urine, pleural and abdominal fluid, tissue cells and other tumor marker tests, early asymptomatic microfocal tumors can be detected in a timely manner. However, a negative tumor marker test does not necessarily exclude tumors, as there are false-positive or false-negative tests, such as some benign diseases, lupus erythematosus and glomerulonephritis and other autoimmune diseases, tumor markers are mostly positive. Therefore, it is necessary to combine with other medical history and auxiliary examination to make a comprehensive judgment, and not to make the diagnosis of “tumor”. In addition, tumor markers are non-specific, that is to say, many different tumors can cause the same tumor marker elevation. At the same time, an elevation of a tumor marker cannot be used to infer that a particular tissue or organ has a tumor. For example, elevated CEA can be seen in smokers, certain benign diseases such as pancreatitis, rectal polyps, ulcerative colitis, peptic ulcer disease, lung infections, diabetes mellitus, as well as lung cancer, gastrointestinal tract tumors and so on. However, if a tumor is diagnosed and treatment is given, monitoring tumor markers can help guide the recurrence or evaluate the effect of treatment. Below are some common tumor markers. 1.AFP(Afetoprotein): elevated in liver cancer, hepatitis, tumors of gonadal origin, such as non-seminomatous germ cell tumors, polycythemia vera, immature teratoma. CA242: elevated in pancreatic cancer, gastric cancer, colorectal cancer, lung cancer and other tumors. 3, CA199: elevated in pancreatic cancer, gallbladder cancer, colon cancer, lung cancer and gastric cancer, CA199>1000U/mL is highly suggestive of cancer and often combined with peritoneal metastasis. 4, CA724: commonly elevated in gastric cancer and other digestive tract tumors. It is also elevated in pancreatitis, liver cirrhosis, lung disease, rheumatism and other benign diseases. 5. CA125: obvious elevation is usually seen in epithelial ovarian cancer. The positive rate of elevated CA125 in the ovary is about 70% or more. Other non-ovarian malignant tumors: 40% of breast cancer, 50% of pancreatic cancer, 47% of gastric cancer, 44% of lung cancer, 32% of colorectal cancer, 43% of other gynecological tumors. Some other benign diseases: endometriosis, pelvic inflammatory disease, ovarian cysts, pancreatitis, hepatitis, cirrhosis, and even early pregnancy, CA125 will be elevated. 6.CA153: commonly used in breast cancer. In conclusion, if you have a tumor, its tumor marker is not necessarily high; if the tumor marker is high, it is not necessarily a tumor. Don’t be overly nervous, find a regular hospital doctor for consultation.