Ligament pain on both sides of the knee can be caused by excessive movement of the knee joint, or it can be caused by degenerative disease of the knee joint. 1. Excessive exercise: The knee joint is a composite joint and a weight-bearing joint in the human body. Regular running, hiking and other physical exercises may cause fatigue injury to the inner and outer ligaments of the knee joint, resulting in pain in the ligaments on both sides of the knee. 2. Degeneration of the knee joint: osteoarthrosis of the knee joint, osteoarthrosis of the knee joint will cause pathologic changes such as osteophytes and synovial hyperplasia in the joints, which on the one hand, may lead to pain in the ligaments on both sides of the knee; on the other hand, if osteophytes appear in the stopping point of the ligaments, it may also lead to the above symptoms. Ligament pain on both sides of the knee may also have other causes, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor.