A bladder nodule is an abnormally enlarged nodule in the bladder that is of unknown nature and requires further testing to determine if it is a benign or malignant nodule. Usually, on physical examination or imaging, the bladder should be smooth with no nodules seen, but if abnormal hyperplastic nodules are present, further biopsy is needed to clarify the nature of the nodule, which may be a polyp, tumor, stone, etc. Further cystoscopy is recommended to directly observe the size and shape of the nodule with the naked eye, whether the surface is smooth and whether there are satellite lesions around it, and to obtain a biopsy under cystoscopy for further laboratory tests to determine the nature of the nodule. If the nodule is benign, a simple surgical resection is sufficient; if it is malignant, a total cystectomy or even a combination of radiotherapy and chemotherapy is required, in addition to surgical resection.