There are many causes of weakness and aching limbs, which can be divided into physiological conditions and pathological conditions. In spring and autumn when you are more sleepy, especially common in women, you may have inexplicable weakness and aching limbs, which may be caused by overexertion after living or exercising during the day, or weakness and aching limbs caused by various factors such as lack of sleep, hot and muggy weather and hunger. In addition to this, pathological factors are most common to first rule out upper respiratory tract infections, such as flu, fever and a series of other problems that cause generalized muscle aches and pains. Some infections of internal organs, such as acute and chronic hepatitis and tuberculosis, may also present with generalized weakness and aches in the early stages. Rheumatoid or rheumatoid arthritis, which occurs in the joints of the limbs, may also cause weakness and soreness all over the body. When this occurs, if there is no recovery in a short period of time, it is best to go to the hospital for active consultation and ask the relevant physician to assist in the diagnosis.