Ankle swelling is a precursor of kidney disease, but it may also be caused by poor venous blood return to the lower extremities, venous thrombosis, cardiac insufficiency, etc. A treatment plan needs to be developed based on the specific cause of the patient’s condition. The examination of lower extremity venous ultrasound as well as renal function, urinary routine, urinary system ultrasound and other items can provide a preliminary understanding of the condition. If the foot swelling is caused by nephritis, you can take oral drugs such as furosemide to diuretic and reduce swelling, and choose drugs to protect the kidney and reduce urine protein for treatment to prevent the aggravation of the disease. In daily life, we should control salt and water intake to avoid water and sodium retention, pay attention not to sit or stand for a long time, and pay attention to a lighter diet, eat less greasy and fried food, and eat more vegetables and fruits appropriately.