For hepatitis B carriers, their hepatitis B surface antibodies are definitely negative, but at this time there is no point in vaccinating against hepatitis B. There will be no hepatitis B surface antibodies because of hepatitis B vaccination. The hepatitis B virus carrier treatment suggestions are as follows: 1, regular review: about once every six months, there are uncomfortable symptoms should be reviewed at any time, the review items mainly include liver function, hepatitis B five quantitative, hepatitis B virus DNA quantitative, fetoprotein, liver ultrasound, liver elasticity measurement, etc., can be timely detection of antiviral treatment indications; 2, antiviral treatment: reach antiviral treatment indications should be timely anti Hepatitis B virus treatment, you can choose interferon, nucleoside analogues, etc. If hepatitis B virus carriers do not undergo antiviral treatment in time, the disease can continue to progress, such as the emergence of hepatitis, cirrhosis, and even liver cancer.