What is gangrene? Many people do not know, the following experts to explain: gangrene is a chronic peripheral vascular disease that occurs at the end of the extremities, and in severe cases, the toes (knuckles) gangrene off, also known as desmoplastic gangrene. Its clinical features are the end of the limbs, the lower extremities are more common, initially the end of the affected limb cold, cold, pale, numb, can be accompanied by intermittent limp, followed by severe pain, the affected toe (finger) necrosis becomes black, and even toe (finger) joints fall off. It occurs in young and strong men, elderly people or diabetic patients. In the book “Ling Shu? The disease is described in the book “Canker Sore”, which says: “When it occurs on the toes, it is called canker sore, and its appearance is red and black, and the cure is death. The treatment does not fail, the urgent chopping, not is dead.” This includes thrombo-occlusive vasculitis, atherosclerotic occlusive disease and diabetic foot. From the above we can see that gangrene is a very serious disease, so we must pay attention to it!