Systemic vasculitis, which may not be well understood by many people, is a group of autoimmune diseases that result in multisystem damage due to inflammation and necrosis of the vessel wall. The clinical manifestations of this group of diseases are complex, varied, and easily misdiagnosed, and most are difficult to diagnose. So what kind of symptoms are likely to have systemic vasculitis? 1. General: fever, weight loss weakness, fatigue. 2, musculoskeletal: arthralgia, arthritis 3, skin: palpable purpura, nodular urticaria, reticulobulbar superficial phlebitis, ischemic skin lesions 4.Nervous system: headache, stroke, single or polyneuritis. 5.Head and neck: sinusitis, nasal chondritis, otitis, iritis. 6.Renal: nephritis, renal infarction, hypertension. 7.Lungs: hemoptysis, pulmonary infiltrative lesions of nodules in the lungs pulmonary phlebitis. 8, laboratory abnormalities: anemia, increased sedimentation, abnormal liver function positive blood urine ANA positive RF positive blood. Cold globulin positive hypocomplementemia, ANCA antibody positive angiotensin converting enzyme activity is elevated. Then the above manifestations are not specific, other conditions can also cause the above various discomforts. To confirm the diagnosis, relevant tests need to be done. However, it is important not to be negligent, which can lead to more serious consequences. The treatment of systemic vasculitis must be hard, accurate and stable!