Patients with positive postoperative margins for prostate cancer require close postoperative follow-up and adjuvant endocrine therapy.
Specifically:
After radical prostate cancer surgery you can sometimes see postoperative pathology reports suggesting “positive prostate margins”, such as descriptions of positive prostate margins at the tip, base, etc.
So what is a positive prostate margin?
What is a positive prostate margin?
A positive prostate margin is commonly understood to mean:
- Tumor cells can still be seen at the border of the tumor organ tissue cut from the body, which often indicates that the tumor is not or has not been removed cleanly;
- There are also a significant number of patients whose tumors have grown right to the edge of resection, and there is no tumor tissue left in the body.
Overall, a positive cut margin is indicative of a locally advanced tumor.
Patients with positive margins after prostate cancer surgery should be followed up closely after surgery. The patient should be given various adjuvant treatments such as endocrine therapy, adjuvant radiotherapy in the area of prostate surgery or early systemic chemotherapy depending on the patient’s physical condition and pathology.
Even when PSA reaches a radical level, many physicians advocate adjuvant endocrine therapy for 12 to 18 months to delay tumor recurrence and progression.