Prostate cancer spread indicates that prostate cancer has developed invasion of surrounding tissues, metastasis of regional lymph nodes, and even metastasis of distant organ tissues such as bone, either of which is a sign of stage IV prostate cancer. This is when the possibility of surgical cure is basically lost and most patients are treated with endocrine therapy.
Because prostate cancer is a relatively inert malignancy, even if it is already stage IV prostate cancer, the five-year survival rate still reaches more than half, with some patients surviving for more than a decade. As the disease progresses, limited prostate cancer can develop distant metastases, and hormone-sensitive prostate cancer can develop into hormone-insensitive, depot-resistant prostate cancer. Fortunately, the advent of drugs such as abiraterone has allowed this group of patients to have their disease under control, extending the survival of prostate cancer patients. But eventually these newer drugs will also fail, thus entering the end stage of prostate cancer with unremitting and irreversible disease progression.
It should be noted that although the five-year survival rate for prostate cancer is high, this is a result of big statistics, and for individuals, there are those who live for 10 years and those who live for one or two years, and it is much more useful to be actively treated by your doctor and to keep an optimistic outlook than to worry about the prognosis.