Focal segmental glomerulosclerosis is a pathological type of chronic nephritis nephrotic syndrome, which is relatively severe. It is called focal segmental glomerulosclerosis because less than 50% of the glomeruli in the kidney are sclerotic, and less than half of the individual glomeruli are sclerotic. Sclerosis is actually equivalent to scarring, and there is no way to reverse the sclerosis, so the treatment effect is relatively poor, even with hormones and immunosuppressive drugs, the probability that focal segmental glomerulosclerosis can be controlled is not more than 50%, and the effect will be slow and take a long time, with the effect of drugs used for more than 3 months to be somewhat effective. Microscopic lesions generally have effects after 2-3 weeks of hormone use, and many patients can even be completely relieved, and the urinary routine is completely normal. In contrast, focal segmental glomerulosclerosis treatment is less effective, more than half will not be controlled, and will eventually develop into chronic renal failure, uremia.