A large lump on the neck may be caused by goiter, enlarged lymph nodes in the neck, sebaceous cysts and other reasons. 1. Goiter: Goiter is mainly related to iodine intake, heredity, infection, autoimmunity and other factors, manifested as a large lump in front of the neck, and the lump will move up and down with swallowing. 2. Swollen lymph nodes in the neck: swollen lymph nodes in the neck are mostly triggered by disease factors, commonly inflammatory diseases, tumor factors, cellular tissue proliferation factors, etc., which can occur anywhere in the neck. 3. Sebaceous cysts: When the sebaceous gland ducts in the skin of the neck area are blocked, sebum gradually accumulates and forms retention cysts, thus triggering sebaceous cysts, which manifest themselves as bumps of varying sizes, medium hardness or elasticity. A large lump on the neck may also have other causes, it is recommended to go to the hospital in a timely manner to improve the examination, to clarify the cause of the disease and then symptomatic treatment.