Cleft lip is commonly known as “hare lip”. The causes of cleft lip in babies can be analyzed from the aspects of genetic factors and environmental factors.
1. Genetic factors: Some children with cleft palate or cleft lip are found to have similar deformities in their immediate or collateral family members, and thus it is recognized that the occurrence of cleft lip has a certain relationship with genetic factors.
2. Environmental factors:
(1) Viral infections: for example, infection with viruses that can cause malformations, such as murine rubella, may trigger cleft lip.
(2) Nutritional deficiencies: there is a clear impact of metabolites for folic acid, as well as riboflavin, pantothenic acid, etc., the lack of such nutrition, can also trigger cleft lip.
(3) Physical factors: in the first trimester of pregnancy, long-term exposure to radioactive substances will increase the probability of teratogenicity.
(4) Drug factors: the application of methotrexate and phenylephrine by pregnant women may cause fetal malformation.
(5) Other factors: for example, smoking, alcoholism, maternal injury, exposure to toxic substances, etc., can also lead to fetal malformation, which in turn leads to cleft lip.
The causes of cleft lip are complex. When this condition occurs, it is important to seek timely medical treatment and standardize the treatment under the guidance of the doctor.