Knee joint replacement usually costs from$50,000 to$100,000. The cost of treatment mainly includes the following: First, the cost of artificial joint materials ranges from$30,000 to$80,000, including lateral femoral prosthesis, tibial plateau prosthesis, polyethylene spacer, sterile rinse gun and bone cement. Second, anesthesia and surgery fees, usually choose general anesthesia or combined lumbar and rigid anesthesia, the cost is about 10,000 yuan. Third, the cost of routine pre-surgical examination, blood transfusion during surgery and post-operative medication is about 10,000 RMB. In summary, the main part of the cost of knee replacement is the cost of artificial joint materials. Ways to reduce the overall cost include insisting on functional exercises for the muscles around the knee joint before surgery, improving quadriceps atrophy, strengthening systemic nutrition, and treating internal diseases. If physical conditions allow, blood transfusion can be dispensed with during surgery and replaced with combined lumbar and rigid anesthesia.