Headache after taking Nicorandil can be reduced, stopped and adjusted under the supervision of a doctor. Nicorandil is mainly used in the treatment of angina pectoris and has the effect of dilating blood vessels, it may cause headache. If the symptoms of headache are not serious and there are no other obvious side effects, you may consider observing it for a while or reducing the dosage of Nicorandil slightly. If the symptoms of headache are severe, you need to stop taking Nicorandil immediately and change to other medications that improve coronary blood supply and treat angina under your doctor’s supervision. In addition to headache, Nicorandil may have side effects such as dizziness, nausea, and panic, and is contraindicated in patients with closed-angle glaucoma. If headache occurs while taking the drug, you need to go to the hospital, the doctor will determine whether the headache is related to the use of this drug, and whether it is necessary to switch to other drugs.