Targeted drugs for soft tissue sarcoma are divided into three categories, which are anti-angiogenic drugs, anti-cell proliferation drugs and immune drugs. 1. Anti-angiogenic drugs inhibit tumor growth by inhibiting tumor angiogenesis, and common drugs such as bevacizumab, sunitinib, pazopanib and other drugs targeting VEGF. 2. Anti-cell proliferation drugs inhibit tumor growth by inhibiting a certain process in tumor cells, commonly used drugs include everolimus, diphosgene and sirolimus. 3. Immune drugs are used to inhibit the immune evasion mechanism of the tumor by inhibiting the expression of cell surface receptors, and the commonly used drugs are pabolizumab and so on. Patients with soft tissue sarcoma should use drugs correctly under the guidance of doctors.