The ingredient of Shihuida is levamlodipine benzenesulfonate, and the ingredient of Bayxin Tong is nifedipine controlled-release tablets. It is impossible to assess which one of the two medicines is better, and it depends on which one of the medicines is more suitable for the patient. Levamlodipine benzenesulfonate and nifedipine controlled-release tablets are calcium antagonists, the main role is to dilate peripheral blood vessels, the main indication is hypertension, and can increase the blood supply of coronary arteries, can also be used in the treatment of coronary heart disease. The two drugs can not assess the efficacy of the good and bad, for hypertension and coronary heart disease has a good therapeutic effect, different patients have different responses to the drug, so it is not possible to directly compare the therapeutic effect of the two drugs. The adverse reactions of levamlodipine benzenesulfonate and nifedipine controlled-release tablets include lower limb edema, tachycardia, dry stools, flushing and so on, and they are forbidden for patients who are allergic to the drug components, severe aortic stenosis and low blood pressure. When clinically choosing levamlodipine benzenesulfonate and nifedipine controlled-release tablets to lower blood pressure, it is important to choose the drug under the guidance of the physician, and choose the most appropriate drug according to the patient’s condition.