Enalapril maleate and nifedipine can be taken at the same time, and the combination of the two can enhance the blood pressure-lowering effect, and should be used under the guidance of a doctor. Enalapril maleate is an angiotensin-converting enzyme inhibitor (ACEI), which can inhibit angiotensin production, inhibit its vasoconstrictor and promote aldosterone secretion effects, and play a role in lowering blood pressure. Nifedipine is a dihydropyridine calcium channel antagonist (CCB), which has the effect of dilating coronary arteries and peripheral vasculature, lowering blood pressure and relieving angina. Both can be taken at the same time, can enhance the effect of blood pressure lowering, in line with the first-line program of combined hypertension dihydropyridine CCB + ACEI, should be used under the guidance of a doctor, for single drug control of blood pressure is not effective, etc.. It should be noted that enalapril maleate is contraindicated in people with a history of allergy to the use of such drugs, or in patients suffering from hereditary or idiopathic angioneurotic edema, and should not be used in pregnant or lactating women. The use of the drug can cause dizziness, headache, hypotension, cough, and even kidney damage and other adverse reactions. Nifedipine is contraindicated in contraindicated in cardiogenic shock, pregnant and lactating women within 20 weeks of pregnancy, and should not be combined with rifampicin. Adverse reactions such as edema, headache, constipation, palpitations and hypotension may occur after use. If Enalapril Maleate and Nifedipine are to be used in combination, they must be used under the supervision of a doctor, and the dosage should not be added or adjusted arbitrarily. If discomfort occurs during the use of the drug, seek medical advice immediately.