Elderly people with swollen ankles in the afternoon may be related to physiological reasons such as walking for a long time or pathological reasons such as kidney disease, heart disease and vascular disease. 1. Physiological reasons: if the elderly walk too long in the morning, it may affect the blood return and ankle swelling occurs. 2. Pathological reasons: Kidney diseases such as nephritis can cause ankle swelling in the afternoon due to decreased filtration rate or sodium retention caused by hypoproteinemia; heart diseases such as heart failure can cause ankle swelling due to sodium retention; when suffering from varicose veins in the lower limbs, ankle swelling can occur due to impaired blood return. It is recommended that elderly people with swollen ankles in the afternoon and accompanied by other discomforts go to the regular hospital in a timely manner, to clarify the cause of the disease and standardize the treatment under the guidance of the doctor.